Trusted by NICUs for feeding 125,000+ preemies. Ask your care team for Prolacta by name.

Bring Your Preemie Home Sooner

Prolacta Nutritional Fortifiers are Clinically proven to help preemies go home sooner

Prolacta's nutritional fortifiers and formulas are the only ones in the U.S. made from 100% donor breastmilk (instead of cow milk), to help your preemie grow strong and thrive.

  • Clinically proven to help preemies go home sooner[1]

  • Improves preemie growth and development[6,7,4,3,11]

  • Trusted by leading NICUs for feeding the smallest preemies[15]

When used as part of an exclusive human milk diet for preemies <2.75 lbs.

Bring Your Preemie
Home Sooner

Prolacta's nutritional fortifiers and formulas are the only ones in the U.S. made from 100% donor breastmilk (instead of cow milk), to help your preemie grow strong and thrive.

  • Clinically proven to help preemies go home sooner1

  • Improves preemie growth and development3,4,6,7,11

  • Trusted by leading NICUs for feeding the smallest preemies15

When used as part of an exclusive human milk diet for preemies <2.75 lbs.

Safe Nutrition for the Smallest Preemies

Prolacta's 100% breastmilk-based fortifiers and formulas are shown to improve health, growth, and development while decreasing the most-common complications of prematurity.

In babies weighing <2.75 lbs, compared to cow milk-based products. 1,2,3,6,8,10,11

Prolacta is Trusted by NICUs for the smallest preemies

TRUSTED BY NICUs

NICU Proven

Used in NICUs nationwide for the smallest preemies.15

Created for PreemieProlacta Fortifier is created for the smallest Preemiess

CREATED FOR Preemies

Created for Preemies

Our fortifiers and formulas provide the vital calories, protein, and nutrients that the smallest preemies need to grow and thrive.4,6,7

Prolacta Fortifier is available overnight by prescription

Available Overnight

FDA Approved

Shipped overnight by prescription to U.S. hospital NICUs since 2006.

Support When You Need It Most

Navigating NICU nutrition can feel overwhelming. Our team can provide info and guidance to help you understand your options. Call 1-888-670-8483 anytime.

If your preemie is born weighing <2.75 lbs, a fortifier will be mixed with breastmilk to provide the extra calories and protein they need to grow. Understanding your nutrition options in the NICU will help you and your care team make the right choice for your baby.

Support When You Need It Most

Navigating NICU nutrition can feel overwhelming. Our team can provide info and guidance to help you understand your options. Call 1-888-670-8483 anytime.

Prolacta Baby Kallie | Born 24 weeks | Birth weight 13.1 oz | Days in the NICU 150

Baby Kallie | Born: 24 weeks | Birth weight: 13.1 oz | Days in the NICU: 150

Why Your Preemie Needs 100% Human Milk

Prolacta baby: Kallie | Born: 24 weeks | Birth weight: 13.1 oz | Days in the NICU: 150

Understanding Your Preemie's Nutrition Options

Preemies need 20-40% more calories and 2-3x more protein than full-term babies to thrive!5,14 Knowing the available fortifier options helps you make informed decisions with your care team.

The Benefits of Breast Milk-Based Fortifiers & Formulas:

  • Nature's Perfect Protection: Breastmilk is full of immune-boosting properties to help fight infections and help babies grow.14

  • Fewer Complications: Known to reduce the serious complications associated with cow milk-based products, including necrotizing enterocolitis (NEC), lung disease (BPD), and eye conditions (ROP).1,2,6,8,10,12

  • Get Home Sooner: Shown to help preemies grow healthy and leave the NICU sooner.1

Compared to cow milk-based products in preemies weighing <2.75 lbs

Support When You Need It Most

Navigating NICU nutrition can feel overwhelming. Our team can provide info and guidance to help you understand your options. Call 1-888-670-8483 anytime.

Advanced Nutrition Science

Compared to cow milk-based products in preemies <2.75lbs, an exclusive human milk diet (EHMD) with Prolacta’s 100% breastmilk-based nutritional fortifiers, has shown in numerous clinical studies to provide:

Prolacta Nutritional Fortifier for Preemies supports Life Saving Protection

Life-Saving Protection

  • 77% Lower NEC Risk8

  • Lower Mortality Risk9

  • Lower Risk of Infection
    (late onset sepsis)2,12

Prolacta Nutritional Fortifier for Preemies supports Fewer Complications in NICUs

Fewer Complications

  • Less Lung Disease (BPD)1,2,6,10

  • Reduced Eye Disease (ROP)1,2,10,12

  • Improved Long-Term Outcomes3,11

Prolacta Nutritional Fortifier for Preemies supports Growth and Development

Better Growth & Development

  • Achieve Adequate Growth4,6,7

  • Reduced Feeding Issues1

  • Shorter NICU Stays1

Discussing Fortifier Choices with Your Care Team

Preemies under 2.75 lbs need a fortifier added to their feeds for extra calories and protein. Being informed about your nutrition options helps you make the best decision with your preemie's care team.

Join Thousands of Families Who Trust Prolacta

Because when every ounce matters, families and NICUs turn to Prolacta for nutritional support.

Prolacta Baby Jahaan in the NICU. Safe Nutrition for the Smallest Preemies. Prolacta's nutritional fortifiers and formulas are the only ones in the U.S. made from 100% donor breastmilk (instead of cow milk), to help your preemie grow strong and thrive.

Baby Jahaan

Born: 29 weeks | Birth weight: 1 lb 15 oz | Days in the NICU: 61

Born: 29 weeks | Birth weight: 1 lb 15 oz

Days in the NICU: 61

His mom, Twinkle, remembers the fear of those first days:

"I didn’t know if my tiny baby could overcome the challenges ahead."

Then his NICU team started Jahaan on a Prolacta fortifier.

Prolacta Baby Jahaan Home from the NICU. Safe Nutrition for the Smallest Preemies. Prolacta's nutritional fortifiers and formulas are the only ones in the U.S. made from 100% donor breastmilk (instead of cow milk), to help your preemie grow strong and thrive.

The difference was life-changing.

  • Within weeks, Jahaan began to steadily gain weight. His body was absorbing the critical nutrients he needed.

  • He avoided dangerous complications often seen in preemies fed cow milk-based products.

  • Today, Jahaan is a thriving toddler, hitting milestones his parents once only dreamed of.

“I truly believe that the human milk-based fortifier played a big role in Jahaan’s growth and development,” said his mom.

**Any views, opinions, findings, assertions, conclusions or recommendations expressed are solely those of the individual. The content is provided for informational purposes only and should not be taken as medical advice.

Why Prolacta Is the Safe Choice for Your Preemie

There is only one nutritional fortifier in the U.S. made exclusively from 100% donor breastmilk: Prolact+ H2MF® human milk fortifier (human, pasteurized).

Tiny Preemie Holding Dad's Hand in the NICU

Prolacta is shown to:

  • Help preemies catch up on the critical growth they need4,6,7

  • Reduce feeding issues associated with cow milk-based products1

  • Get your baby home from the NICU sooner1

Compared to cow milk-based products in preemies weighing <2.75 lbs

Tiny Preemie Holding Dad's Hand in the NICU. Safe Nutrition for the Smallest Preemies. Prolacta's nutritional fortifiers and formulas are the only ones in the U.S. made from 100% donor breastmilk (instead of cow milk), to help your preemie grow strong and thrive.
Prolacta Babies Baby Eliza and Baby Octavia in the NICU. Safe Nutrition for the Smallest Preemies. Prolacta's nutritional fortifiers and formulas are the only ones in the U.S. made from 100% donor breastmilk (instead of cow milk), to help your preemie grow strong and thrive.

Baby Eliza and Baby Octavia

Born: 28 weeks | Birth weight: 2 lbs 8 oz & 1 lb 14 oz | Days in the NICU: 53 & 63

Born: 28 weeks
Birth weight: 2 lbs 8 oz & 1 lb 14 oz
Days in the NICU: 53 & 63

Eliza and Octavia faced overwhelming odds. Their mom Caytlin recalls the fear:

"They were so tiny—every ounce mattered."

Prolacta Babies Baby Eliza and Baby Octavia After Leaving the NICU. Safe Nutrition for the Smallest Preemies. Prolacta's nutritional fortifiers and formulas are the only ones in the U.S. made from 100% donor breastmilk (instead of cow milk), to help your preemie grow strong and thrive.

Their NICU team chose Prolacta’s 100% breastmilk-based fortifiers and formulas to:

  • Support their growth and development during critical early weeks

  • Help them gain weight steadily despite their micro-preemie size

  • Avoid complications linked to cow milk-based products

“The donor breastmilk and the (Prolacta) human milk fortifiers gave my babies a good start in their NICU journey," said their mom.

**Any views, opinions, findings, assertions, conclusions or recommendations expressed are solely those of the individual. The content is provided for informational purposes only and should not be taken as medical advice.

Baby Aria | Born: 27 weeks | Birth weight: 1 lb 6 oz | Days in NICU: 110

Baby Leah Michelle | Born: 23 weeks | Birth weight: 1 lb 8 oz | Days in NICU: 131

Frequently Asked Questions

How do I know if my preemie qualifies for Prolacta's fortifiers and formulas?

Prolacta's breastmilk-based fortifiers and formulas are typically recommended for preemies weighing less than 2.75 lbs. They can be shipped overnight to any NICU in the U.S. and no hospital contract is required.

In 2024, more than 50% of acute care NICUs in the U.S. used Prolacta’s nutritional products.15 If your hospital isn’t one of them, your NICU can still request our fortifiers be overnighted for even a single baby.

Ask your NICU team if your baby qualifies or contact Prolacta at 1.888.354.5818 for more information.

What if my hospital says they don't carry Prolacta products?

Any NICU can order Prolacta's fortifiers and formulas by prescription, even if they don't routinely stock them. They can be delivered to any NICU in the U.S., often overnight, and with no contract required.

If your hospital doesn’t offer it yet, call our Parent Support Hotline at 1.888.354.5818. We’ll help you understand your options so you can make an informed choice with your care team.

What is a fortifier?

A fortifier is a nutritional boost added to breastmilk to give preemies the extra calories and protein they need to grow. When mixed with your breastmilk, it’s kind of like a preemie protein shake.

BE AWARE – Despite the name designation,"Human Milk Fortifier" (HMF) – all but one brand of fortifiers in the U.S. are made from cow milk. In the U.S., Prolacta is the only brand of "human milk fortifier" made from 100% donor breastmilk, making it a gentle choice for your preemie’s immature digestive system.

What is NEC (necrotizing enterocolitis)?

NEC, or necrotizing enterocolitis, is a serious intestinal disease primarily affecting premature or sick newborns. It causes the lining of the baby’s intestine to become swollen and damaged. In severe cases, the intestinal wall can develop a hole that may require surgery to repair. An exclusive human milk diet including Prolacta’s products are clinically proven to reduce the risk of NEC, protecting fragile babies from this life-threatening disease.1,2,8

What's the difference between the various human milk fortifiers (HMFs)?

While all fortifiers are labeled 'human milk fortifier,' only Prolacta's are made from 100% donor human milk. All others are made from cow milk.

Studies show that an "Exclusive Human Milk Diet" (mom’s own milk or donor milk, if mom’s milk is unavailable, combined with Prolacta’s fortifiers or formulas) is associated with fewer complications, as compared with babies fed a cow-milk based formula or fortifier3, 13, 8

What is an Exclusive Human Milk Diet (EHMD)?

An EHMD means your baby’s diet consists of 100% breastmilk and products made from 100% breastmilk. In the NICU, this includes breastmilk + Prolacta's breastmilk-based fortifiers or formulas. An EHMD is clinically proven to reduce serious complications in preemies compared to diets containing cow milk-based products.1, 2, 8

Last year, over 50% of advanced NICUs in the U.S. used Prolacta’s nutritional products for the smallest preemies in their care[15

Why is breastmilk so important?

Breastmilk is nature's perfect food for your baby. Breastmilk is full of antibodies and other immune-boosting properties to help fight infections, and it is gentle on the immature digestive tract of your premature baby.14 However, breastmilk alone isn't enough for extremely premature babies. They need 20-40% more calories and 2-3x the protein than breastmilk provides.5,14

Prolacta's breastmilk-based fortifiers and formulas add this extra nutrition while maintaining the safety of an exclusive human milk diet, helping these tiny babies grow and go home sooner.1,6,7,4

Will my preemie still get my breastmilk?

If you are able to produce breastmilk, yes, it will still be an important part of your baby's nutrition. Fortifiers simply add the extra calories and protein your baby needs to grow stronger.6,7,4

For moms who can’t produce enough breastmilk, many hospitals offer donor breastmilk, including donor breastmilk from Prolacta and our breastmilk-based Ready to Feed (RTF) formula.

Ready to Learn More About Your Preemie's Nutrition Options?

The nutrition your baby receives in the NICU can shape their health and development long after they come home.

Our Parent Support Team is here to help you understand how Prolacta's fortifiers and formulas might benefit your baby and guide you through the next steps.

Call 1-888-670-8483 to speak with our team, or fill out the form and we'll call you back.

Take the first step.

Fill out the form and a member of our Parent Support Team will reach out—because every preemie deserves access to the best care available.

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Citations

15. Data on file; number of U.S. hospitals that used Prolacta's fortifiers and formulas in 2024.

17. Alganabi M, Lee C, Bindi E, Li B, Pierro A. Recent advances in understanding necrotizing enterocolitis. F1000Res. 2019 Jan 25;8:F1000 Faculty Rev-107. doi: 10.12688/f1000research.17228.1. PMID: 30740215; PMCID: PMC6348433.

Safe Nutrition for the Smallest Preemies. Prolacta's nutritional fortifiers and formulas are the only ones in the U.S. made from 100% donor breastmilk (instead of cow milk), to help your preemie grow strong and thrive.

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